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MEDCHEMEXPRESS LLC TACROLIMUS 10MG
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EMOLECULES INC 111333-HEXAFLUORO-2- 500G
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MEDCHEMEXPRESS LLC 1ALPHA-HYDROXY VD4 1MG
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MEDCHEMEXPRESS LLC PHORBOL 12-MYRISTATE 13-ACETAT
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501873692 PHORBOL 12-MYRISTATE 13-ACETAT
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MEDCHEMEXPRESS LLC DESISOBUTYRYL-CICLESONIDE 5MG
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MEDCHEMEXPRESS LLC PF-4136309 5MG
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MEDCHEMEXPRESS LLC DOCETAXEL SOLID 100MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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501874028 DOCETAXEL SOLID 100MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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MEDCHEMEXPRESS LLC GLY-MCA 5MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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501872522 GLY-MCA 5MG
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MEDCHEMEXPRESS LLC ROSTAFUROXIN 10MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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501872620 ROSTAFUROXIN 10MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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MEDCHEMEXPRESS LLC CHAPS 1G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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501873226 CHAPS 1G
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MEDCHEMEXPRESS LLC INCB 3284 10MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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501873234 INCB 3284 10MG
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Medchemexpress LLC Sri-37330 hydrochloride | 2322245-49-6 | 99.72% | C16H20ClF3N4O2S | 1 G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound can be used for type 2 diabetes research.
- Inhibits human TXNIP promoter activity in INS-1 cells.
- Decreases TXNIP mRNA and protein levels in INS-1 cells.
- Blocks polymerase II binding to the E-box motif of the TXNIP promoter.
- Reduces glucagon secretion in TC1-6 cells.
- Inhibits glucagon-induced glucose output from primary hepatocytes.
- Decreases glucagon secretion and action, and blocks hepatic glucose output in vivo.
- Well tolerated in male C57BL/6J mice.
- Reverses obesity- and STZ-induced diabetes and hepatic steatosis in mice.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound can be used for type 2 diabetes research.
- Inhibits activity of human TXNIP promoter in INS-1 cells.
- Decreases mRNA and protein levels of TXNIP in INS-1 cells.
- Inhibits polymerase II (Pol II) binding to the E-box motif region of the TXNIP promoter.
- Lowers glucagon secretion in TC1-6 cells.
- Inhibits glucagon-induced glucose output from primary hepatocytes.
- Decreases glucagon secretion and action in mice.
- Blocks hepatic glucose output in mice.
- Reverses obesity- and streptozotocin-induced diabetes and hepatic steatosis in mice.
- Well tolerated in male C57BL/6J mice.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More